A New Study Urges Caution In Choosing Metronidazole
Along with the pathogens, most antibiotics also alter the commensal populations needed for health. As a result, important gut microbiome populations can be decimated, leading to dysbiosis. A new study published this year in the Journal of Veterinary Internal Medicine calls attention to metronidazoles dramatic effects on the canine gut microbiome.1
Healthy dogs were medicated with a 14-day course of metronidazole more than 50% developed diarrhea during treatment. The gut microbiome composition changed significantly, and included decreases in important beneficial bacteria, such as Fusobacteria one of the dominant phyla of bacteria in the gut microbiomes of dogs and cats and reductions in overall richness . Effects were not temporary: fourweeks post metronidazole, microbiome changes had not fully resolved, compromising healthy gut function.
The authors recommend that veterinarians adopt a more cautious approach when using metronidazole, particularly in dysbiotic patients.
Metronidazole Use In Dogs For Parasites
As we mentioned previously, metronidazole for dogs may be used for parasitic infections. There are several that can be successfully treated using the medication.
Trichomoniasis is one such infection caused by a protozoa. The parasite is transmitted to your canine through infected feces, and usually another infected canine is the culprit. Like many of the other ailments, trichomoniasis can cause severe diarrhea and bloody stools, and the medicine can stop these symptoms.
Dog diarrhea medicine metronidazole is prescribed when cysts are found in the stool. These cysts are released from the parasite and are used to positively diagnose the infection. Giardia is another parasitic infection treated by metronidazole.
Treatment Of Metronidazole Toxicity
If Metronidazole toxicity is confirmed, the medication will be stopped and your dog will receive therapy to treat the symptoms.
The medication your dog receives will depend on the test results and symptoms, but vets usually prescribe diazepam to relieve vestibular dysfunction and shorten the recovery time.
The vet might also prescribe IV fluids along with nutrients and electrolytes as needed, to flush the kidneys and prevent your dog from getting dehydrated.
They will likely suggest your canine companion be hospitalized for at least 24 hours for supplemental treatment and observation. How long your pooch will stay in the hospital will depend on the severity of the symptoms and how well they respond to the therapy.
Pro tip: Pet insurance covers emergencies related to accidents, such as toxic ingestions. It also includes all sorts of services related to accidents, like MRI, X-rays, bloodwork, ultrasounds, medications, hospitalization, and surgery.
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Metronidazole For Dogs And Cats
- Drug Name: Metronidazole for Dogs and Cats
- Common Name: Flagyl®, Metizol®, Protostat®, Metrogel®
- Drug Type: Antibiotic, antiprotozoal
- Used For: Prevention and treatment of bacterial and parasitic infections
- Species: Dogs, Cats
- Administered: Tablet, Oral liquid, Injectable
- How Dispensed: Prescription only
Can Metronidazole Kill Dogs
At doses that veterinarians usually prescribe, metronidazole typically only causes minor side effects. Many medications can potentially be fatal if a pet consumes large amounts of medications and overdoses. This can occur when a pet eats an entire bottle of medication off of the counter or an owner accidentally administers too much medication to an animal.
Metronidazole at toxic levels can cause severe neurological symptoms including seizures. If dogs overdose on large amounts of metronidazole, it could potentially be fatal. If your dog has ingested more than the prescribed dose of metronidazole, you should call Pet Poison Helpline or ASPCA Poison Control and get your dog to a veterinarian as soon as possible.
If you are curious about other common household items that can cause toxicity in dogs, be sure to check out this article on Common Household Foods That Are Toxic For Your Dog.
The Vet Stamp of Approval
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Guidelines For Safe Use
Metronidazole is considered very safe. However, it should not be prescribed to pregnant bitches or young puppies, and should be considered carefully before being prescribed to dogs that are nursing. It may also not be suitable for pets with kidney disease, liver disease, neutropenia , or seizure disorders.
Before using any medication for your pet, its best to speak to your veterinarian. You should:
- Discuss any other medicine your dog is taking and the dogs medical conditions.
- Be cautious when using the drug for extended periods of time, since adverse effects are more common during long-term use.
- If you are giving your dog metronidazole to remedy diarrhea, be sure to provide lots of fresh water to prevent the dog from becoming dehydrated.
What Is Metronidazole For Cats Used For
Metronidazole is an oral antibiotic used in dogs and cats to kill some intestinal parasites, especially Giardia spp. It is also used to treat diarrhea and infections caused by anerobic bacteria. This medication has a bitter taste.
Also, what parasites does metronidazole kill? The parasitic infection best known to parents is pinworms, but others include malaria, tapeworms, hookworms, and trichinosis. Some antibacterials also work against parasites. Metronidazole can block the reproduction cycle of some parasites as well as some bacteria.
Simply so, how long does metronidazole take to work for cats?
This medication should take effect within 1 to 2 hours, and while effects may not be visibly noticed immediately, but gradual improvements are usually noticable after a few days.
What is prednisolone used for in cats?
Prednisolone is a prescription corticosteroid that is used in dogs and cats to treat various conditions such as Addison’s disease, inflammation from arthritis, allergies and certain autoimmune diseases.
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Which Side Effects Are Life
All medications carry serious risks, including metronidazole, but thankfully they are very rare. These problems are more likely to happen if your dog is taking this medication at high doses or for a long time.
Contact the emergency pet hospital right away if you notice any of the following:
Hives, fast heart rate, or trouble breathing signs of a possible allergic reaction
Changes to emotional behavior, such as seeming more depressed or lethargic than usual
Trouble walking, tremors, enlarged pupils, rapid eye movements or twitching, or seizures
If you suspect that your dog received too much medication, contact the American Society for the Prevention of Cruelty to Animals Animal Poison Control Center at . Please note, a consultation fee may apply for the call.
Potential Side Effects And Risks Of Metronidazole For Dogs
Same as any other drug, Metronidazole can cause side effects in dogs. The most common side effects include nausea, vomiting, and diarrhea. Drooling, blood in the urine and appetite loss are also possible but not as common. If these side effects appear, the vet will prescribe medications for their management.
Plus, the ability of Metronidazole to cross the blood-brain barrier means there is a higher chance of neurological side effects. They can range from mild depression, head tilts, and loss of balance to seizures, lack of coordination, and paralysis in all four legs.
Though paralysis of the legs in dogs is rare, because of the severity, it is definitely worth mentioning. Slight depression and stiffness are also quite common when using Flagyl, however, they are not something to be particularly worried about.
In rare instances, Metronidazole use has been shown to cause pancreatitis in dogs. Prolonged use of this antibiotic can lead to the development of acute pancreatitis in dogs, which can have a domino effect on further gut health.
Finally, we should note that some dogs can be allergic to this antibiotic. Most allergic reactions manifest with hives and rashes. however, in more severe cases, they can trigger swelling of the airways and cause difficulty breathing. This form of allergic reaction is called anaphylactic shock and is considered a medical emergency.
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What If I Miss Giving My Pet The Medication
If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give the medication at the next scheduled time and continue with the regular dosing schedule. Never give your pet two doses at once or give extra doses.
It is very important to give the medication for the length of time your veterinarian has recommended.
Top Best Answers To The Question What Is Metronidazole 250 Mg Used For In Dogs
Metronidazole is used to treat protozoal infections in dogs and cats including Giardia, Entamoeba, Trichomonas, and Balantidium. It also is used to treat anaerobic bacterial infections. Metronidazole has immune-modulating activity and may be prescribed to treat inflammatory bowel disease.
Metronidazole is used primarily as an anti-diarrheal medication for dogs, but it is also prescribed to treat protozoal infections including Balantidium Coli, Giardia, and Trichomonas, as well as anaerobic bacterial pathogens.
Those who are looking for an answer to the question «What is metronidazole 250 mg used for in dogs?» often ask the followingquestions:
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Our Final Thoughts On Metronidazole For Dogs
In addition to being safe, Metronidazole used for diarrhea and other conditions is efficient. As a matter of fact, dog Metronidazole is versatile and can be used to fight off various infections and conditions.
However, every dog is different, and every situation requires a different approach. In those terms, keep in mind that this article is purely informative and should not be used as a substitute for visiting the vet and requiring a professional opinion.
Giving Your Cat Metronidazole A Technique
Cats hate the taste of Metronidazole. No, they REALLY hate the taste of metronidazole. If you are unfortunate enough to have to dose your pet with this loathsome substance, you likely have already discovered that after the first dose given to your sweet and unsuspecting little kitty, the second and following doses go much, much worse.
My little angel, Smith, has had to have several courses as he has spent the last four years struggling with some intestinal ailment. His reactions have ranged from a) digging a claw out of the cat burrito and inserting it firming into the hand with the syringe or pill and pulling firmly. b) sinking his teeth into the hand with the syringe or pill c) holding the pill in his mouth while drooling furiously for as long as I cared to hold him, at which case he would eject any remaining undissolved portion. d) Running furiously from me and cowering under things yowling at the top of his lungs when he heard the pill bottle…………. you get the idea.
He was the absolute worst to dose, and I literally thought one of us might not survive the course of medicine. And not because of his ailment.
So, eventually, common sense sunk in. I had a hard time taking pills as a child. I had difficulty swallowing them and they would stick in my throat. My mother used to use applesauce to help with this. Cats, of course, do not like apple sauce, and MY cats wouldnt eat a pill pocket if they were starving.
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Inappropriate Uses Of Metronidazole
Because past research has found metronidazole to be effective against certain causes of diarrhea in dogs, it has become many veterinarians go-to treatment for diarrhea in general. The problem is that there isnt much scientific evidence that metronidazole actually helps some of the conditions its being used for. And yet, even without strong scientific evidence of its effectiveness, metronidazole has become the most commonly prescribed antimicrobial agent for acute diarrhea in dogs.3 Here are three common situations in which research has found metronidazole to be the wrong choice.
In the past, metronidazole was commonly used to treat infections caused by the protozoan parasites Giardia and Tritrichomonas, which are known to cause diarrhea in cats and dogs. Over time, however, both these organisms have developed metronidazole resistance, so this medication by itself is no longer a curative treatment for these protozoal infections. 46
Inflammatory bowel disease
Because metronidazole has a positive effect on Crohns disease in humans, it is often used for diarrhea in dogs with IBD and other chronic diseases of the intestines, usually in combination with the steroid prednisone.47 However, researchers established in 2010 that metronidazole doesnt actually add any benefit in this scenario: prednisone plus metronidazole is no more effective for IBD than prednisone by itself.4
How To Store Metronidazole For Cats
Metronidazole tablets and capsules should be stored in a tightly sealed container at a temperature below below 30°C . Remember to always keep them away from the sunlight. A cabinet or drawer is a great option.
For the liquid formulations, these should be stored in the refrigerator. However, if your vet has made a special formulation, it’s best to ask them how to store it and follow the instructions provided.
This article is purely informative. AnimalWised does not have the authority to prescribe any veterinary treatment or create a diagnosis. We invite you to take your pet to the veterinarian if they are suffering from any condition or pain.
If you want to read similar articles to Metronidazole for Cats With Diarrhea, we recommend you visit our Medicine category.
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Side Effects Of Metronidazole For Dogs
Metronidazole is considered to be safe for dogs when administered properly and rarely causes side effects. The list of common possible side effects includes:
Less common side effects include:
- Irregular or abnormally slow heartbeat
- Dilated pupils
The drug can also cause neurological symptoms such as :
- Loss of balance and coordination
- Head tilt
- Stumbling or knuckling
- Strange behavior
As with all drugs, theres a possibility of an allergic reaction that can result in anaphylaxis. “Anaphylaxis in Dogs | VCA Animal Hospital”), a potentially life-threatening condition. Signs of an allergic reaction include rash, hives, rapid heartbeat, difficulty breathing, and swelling.
Puppies and pregnant pups, as well as pups with a history of kidney or liver disease, those who have seizure disorders or from neutropenia, as well as dogs who had an adverse reaction to the drug in the past, shouldnt take Metronidazole. Be sure to let your vet know if your dog suffers from any of these conditions or is taking any other medications, including vitamins, herbal therapies, or supplements.
Veterinary journals say that most cases of Metronidazole toxicity involve very high doses or chronic use of the drug.
Are There Any Life
Just as with any medication, metronidazole does have certain risks and serious side effects to be aware of. While these complications can happen with any dose, they are more likely to occur if your cat is taking high doses of metronidazole over a long period of time.
Seek emergency veterinary care as soon as possible if you notice any of the following signs:
- Hives, fast heart rate, trouble breathing, or other signs of an allergic reaction
- Behavior changes, including seeming more depressed or tired than usual
- Trouble walking, tremors, enlarged pupils, rapid eye movements or twitching, or seizures
These severe side effects may not appear for a few days after starting metronidazole, so be sure to watch for them the entire time your cat is taking the medication. Thankfully, these side effects usually go away once the medication is stopped. Be aware, though, that even after stopping metronidazole, it may take up to two weeks for nerve-related side effects to completely resolve.
If you are afraid your cat is experiencing an overdose, contact an emergency vet hospital near you or call the American Society for the Prevention of Cruelty to Animals Animal Poison Control Center at . Please note, a consultation fee may apply for the call.
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Are Medications Always Necessary To Treat Diarrhea In Dogs
No. Supportive care like diet changes, adequate hydration, introduction of fiber, and use of probiotics is sometimes tried before medications. For example, during the first 12 to 24 hours of diarrhea, your vet may recommend withholding food or providing small meals every few hours.
Dietary changes may include adding fiber or trying hypoallergenic dog food if your vet feels a food allergy might be the culprit. Canned pumpkin is an excellent source of fiber you can add to your dogs meal. Your vet may also recommend adding fiber with Metamucil or coarse wheat bran.
You may also be instructed to make these dietary suggestions along with antibiotics like metronidazole. Regardless of whether you are providing your dog medications, supportive care, or both, the most important thing is to follow your vets recommendations. This will help ensure your furry friend gets back to feeling like themself as quickly as possible.
Metronidazole Dosage For Dogs And Cats
The dosage for metronidazole in dogs and cats varies depending on its intended use and the specifics of a patients case. A dose range of between 5 and 25 mg/lb given by mouth is typical. Higher doses may be given once daily, while lower doses are generally given twice daily. Always follow the specific dosing instructions provided on the label of your pets medication and contact your veterinarian with any questions or concerns.
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Can I Give My Dog Metronidazole
Yes, you can give your dog Metronidazole. However, you will need a veterinary prescription, and you will have to use the medication following the vets instructions and guidance.
The good news is that Metronidazole is safe for dogs, easy to use, and readily available. Plus, it can be used to manage various conditions but mostly different causes of diarrhea .
Simply put, Metronidazole is a highly valued antibiotic with proven antibacterial and antiprotozoal properties.